Product Profile—Acetyl Hexapeptide-1, Melitane
Kallikrein and antimicrobial compounds such as antimicrobial peptides play an important role in the natural response of the immune system to potentially harmful substances and environments. They can induce the release of interleukin (IL), but excessive amounts of IL may cause facial redness and dilation of blood capillary cells. Erythema and vasodilatory dermatoses, such as rosacea, have abnormally high expression of LL-37, which, when activated, leads to an increase in pro-inflammatory metabolites, including IL-6 and IL-8. When the extra cellular matrix such as collagen is hydrolyzed by MMPs, the connective tissue of the dermis is destroyed. As a result, areas of redness become more visible, blood capillaries become weaker and more permeable, and inflammation is more likely to cause blood capillary dilation.
Product parameters—Acetyl Hexapeptide-1, Melitane
| Chinese name：乙酰基六肽-1 | English name：Palmitoyl Tripeptide-1 / Pal-GHK |
| CAS No.：448944-47-6 | Purity：≥98% |
| Molecular weight ：870.01g/mol | Molecular Formula：C43H59N13O7 |
| Appearance：White powder | Storage conditions: sealed, stored at -20 ° C |
| Packing specifications (powder): 1g, 10g, 100g | Application: Cosmetic raw material |
Efficacy and application––Acetyl Hexapeptide-1, Melitane
1. Hair Pigmentation and Reversing the Process of Greying
2. Induced skin pigmentation
3. Enhances the skin’s defense against UV damage
4. Reduce red spots on the skin
5. Reduces inflammatory response
6. Protect and repair DNA damage caused by violet rays
Mechanism of action— Acetyl Hexapeptide-1, Melitane
Acetyl-hexapeptide-1 (Acetyl-hexapeptide-1), which has affinity for MC1-R, is a biomimetic peptide mimicking α-MSH. It can promote melanin production by binding to MC1-R, so it can act as a natural photoprotective factor and inflammatory modulator. At the same time, it can also promote melanin transfer from melanocytes to keratinocytes, so it can promote skin or hair coloring.